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Search Results for " squalene epoxidase "

13

Compounds

Cat No. Product Name Synonyms Targets
T1497 Liranaftate Piritetrate,M-732 Antifungal
Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is ...
T6702 Terbinafine Terbinex,SF 86-327,Lamisil,TDT 067 Antibacterial , Antibiotic , Antifungal
Terbinafine (TDT 067) is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important c...
T1411 Terbinafine hydrochloride KWD 2019,Terbinafine HCl,TDT 067 hydrochloride Antibacterial , Antibiotic , Antifungal
Terbinafine hydrochloride (KWD 2019) is a synthetic allylamine derivative structurally related to naftifine. Terbinafine is active against dermatophytes.
TQ0115 NB-598 Antifungal
NB-598 is an effective and competitive inhibitor of squalene epoxidase. It suppresses triglyceride biosynthesis through the farnesol pathway.
T1217 Butenafine hydrochloride KP363 (Hydrochloride),Butenafine HCl,KP-363 Antibiotic , Antifungal
Butenafine hydrochloride (KP363 Hydrochloride) is a synthetic benzylamine antifungal, inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
T11321 FR194738 free base Antifungal
FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. 
T83658 SQLE-IN-1 Antifungal
SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the...
T1543 Naftifine hydrochloride Naftifungin,Naftifine HCl,Naftin,Exoderil Hedgehog/Smoothened , Antibiotic , Antifungal
Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its...
T12199 NB-598 Maleate Others
NB-598 Maleate is a competitive squalene epoxidase (SE) inhibitor.
T12199L NB-598 hydrochloride Antifungal
NB-598 hydrochloride is a competitive squalene epoxidase (SE) inhibitor.
T21365 Butenafine KP363,KP 363,Mentax,KP-363,Butop
Butenafine hydrochloride is a hydrochloride of butenafine, which inhibits squalene epoxidase to inhibit the synthesis of ergosterol, leading to the increased permeability of the cell membranes, allowing their contents to...
T11320 FR194738 Antifungal
FR194738 is an inhibitor of squalene epoxidase with an IC50 of 9.8 nM in HepG2 cell homogenates.
T6702L Terbinafine lactate DRG-0286,Terbinafine hydrochloride,Lamisil Krem,SF 86-327 hydrochloride,Lamisil,Lamisil AT
Terbinafine, a synthetic allylamine antifungal, inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway.
TargetMol