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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1497 | Liranaftate | Piritetrate,M-732 | Antifungal |
Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is ... | |||
T6702 | Terbinafine | Terbinex,SF 86-327,Lamisil,TDT 067 | Antibacterial , Antibiotic , Antifungal |
Terbinafine (TDT 067) is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important c... | |||
T1411 | Terbinafine hydrochloride | KWD 2019,Terbinafine HCl,TDT 067 hydrochloride | Antibacterial , Antibiotic , Antifungal |
Terbinafine hydrochloride (KWD 2019) is a synthetic allylamine derivative structurally related to naftifine. Terbinafine is active against dermatophytes. | |||
TQ0115 | NB-598 | Antifungal | |
NB-598 is an effective and competitive inhibitor of squalene epoxidase. It suppresses triglyceride biosynthesis through the farnesol pathway. | |||
T1217 | Butenafine hydrochloride | KP363 (Hydrochloride),Butenafine HCl,KP-363 | Antibiotic , Antifungal |
Butenafine hydrochloride (KP363 Hydrochloride) is a synthetic benzylamine antifungal, inhibiting the synthesis of sterols by inhibiting squalene epoxidase. | |||
T11321 | FR194738 free base | Antifungal | |
FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. | |||
T83658 | SQLE-IN-1 | Antifungal | |
SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the... | |||
T1543 | Naftifine hydrochloride | Naftifungin,Naftifine HCl,Naftin,Exoderil | Hedgehog/Smoothened , Antibiotic , Antifungal |
Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its... | |||
T12199 | NB-598 Maleate | Others | |
NB-598 Maleate is a competitive squalene epoxidase (SE) inhibitor. | |||
T12199L | NB-598 hydrochloride | Antifungal | |
NB-598 hydrochloride is a competitive squalene epoxidase (SE) inhibitor. | |||
T21365 | Butenafine | KP363,KP 363,Mentax,KP-363,Butop | |
Butenafine hydrochloride is a hydrochloride of butenafine, which inhibits squalene epoxidase to inhibit the synthesis of ergosterol, leading to the increased permeability of the cell membranes, allowing their contents to... | |||
T11320 | FR194738 | Antifungal | |
FR194738 is an inhibitor of squalene epoxidase with an IC50 of 9.8 nM in HepG2 cell homogenates. | |||
T6702L | Terbinafine lactate | DRG-0286,Terbinafine hydrochloride,Lamisil Krem,SF 86-327 hydrochloride,Lamisil,Lamisil AT | |
Terbinafine, a synthetic allylamine antifungal, inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. |